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KMID : 1231220230140020041
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Journal of the Korean Society for Research on Nicotine and Tobacco
2023 Volume.14 No. 2 p.41 ~ p.48
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Korean Clinical Practice Guideline for Smoking essation Provided by the National Health Insurance Services
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Seo Yoo-Bin
Paek Yu-Jin
Lee Cheol-Min
Lee Eon-Sook
Kang Hye-Seon
Kim Soo-Young
Roh Sung-Won
Park Dong-Won
An Yoo-Suk
Jo Sang-Ho
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Abstract
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Background: An evidence-based guideline was formed that addresses several questions regarding pharmacotherapy for smoking cessation among tobacco-dependent adults.
Methods: The multidisciplinary guideline panel selected seven clinical key questions and adopted the Grading of
Recommendations Assessment, Development, and Evaluation (GRADE)-ADOLOPMENT methodology. The recommendations were verified through literature search and selection, evidence synthesis and evaluation, and the recommendation grade selection process.
Results: For smoking cessation in general population, our recommendation is to use varenicline rather than the nicotine patch or bupropion. We conditionally suggest combining varenicline with a nicotine patch instead of using varenicline alone. As for the duration of treatment, we recommend using extended-duration therapy (more than 12 weeks) rather than standard-duration therapy (6-12 weeks). For tobacco-dependent adults who are not yet ready to quit smoking, we recommend initiating treatment with varenicline rather than waiting for them to be ready. In special populations, for adults with a comorbid psychiatric condition, varenicline is preferred over the nicotine patch. Additionally, pharmacotherapy is strongly recommended for adults with chronic obstructive pulmonary disease.
Conclusion: Seven recommendations that focused on drug treatment for smoking cessation were developed. Moreover, the guideline panel expects that following these guidelines will increase the effectiveness of smoking cessation intervention.
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KEYWORD
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Smoking cessation, Practice guideline, Pharmacotherapy
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